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IGNOU BCHET-149 (January 2025 – December 2025) Assignment Questions

Part-A

1. a) Describe the biochemical composition of a living organism

b) Explain the structure and functions of mitochondria.

2. a) Why do monosaccharides form cyclic structure? Draw the structures of open chain and cyclic forms of glucose.

b) Taking D-glucose as an example explain the term mutarotation.

3. a) What is the principal structural difference between amylose and cellulose? Explain giving structures.

b) What is the difference between a fat and a fatty acid? Give definition of iodine number.

4. a) Describe the structural differences between a triacylglycerol and a phospholipid. Give one example in each case.

b) What are the similarities in composition amongst the four DNA nucleotides.

5. a) Describe the isoelectric point. With the help of an example explain the utility of this property of amino acids and how is it useful in maintaining pH in human systems.

b) How are the peptides named? Write the structure of a tripeptide of your choice and write its full and abbreviated name.

Part-B

6. a) What is meant by active site of an enzyme? How do the binding groups and catalytic groups of an active site differ from each other?

b) What is the basic principle involved in the mechanism of enzyme action in biological reactions? Explain.

7. a) What is the significance of oxidative phosphorylation? Illustrate with the help of two examples. b) How is the enzyme, pyruvate dehydrogenase complex different from other enzymes? How does it function in the conversion of pyruvate to acetyl- CoA?

8. a) What are the similarities between DNA replication and RNA transcription?

b) Describe the factors that affect the immune response.

9. a) Describe the interrelationship amongst the metabolic pathways.

b) Write the steps of the degradation of amino acids and give a diagrammatic representation.

10. a) Describe the energetic of the degradation of fatty acids.

b) Explain the mechanism of drug action.

IGNOU BCHET-149 (January 2024 – December 2024) Assignment Questions

Part-A

1. a) Differentiate between a prokaryotic and a eukaryotic cell in terms of their structure.
b) How are lysosomes formed in the cells. Describe their role within the cell.

2. a) What do capital letters D and L signify in the context stereochemistry of monosaccharides? Explain with the help of an example.
b) Write a reaction that is used in distinguishing an aldose from a ketose. How does an aldose react with phenylhydrazine? Give the reaction involved and explain.

3. a) What is milk sugar? How is it formed? Explain giving the reaction.
b) How are amino acids represented? Explain with the help of an example. Describe in brief the configuration of amino acids.

4. a) Describe the behaviour of amino acids in acidic and basic medium. What is the significance of their Zwitterionic Nature?
b) How is peptide bond formed? Explain the stereochemistry of a peptide bond.

5. a) Describe in brief the Merrifield solid phase synthesis of peptides.
b) Describe the covalent interactions involved in protein folding.

Part-B

6. a) Explain the physiological aspect of specificity of enzyme action that distinguishes it from the non-enzyme part in a catalyst.
b) What is Michaelis-Menton equation? Describe its significance in affecting the rate of an enzymatic reaction.

7. a) Describe the structural and functional basis of classification of lipids.
b) What are phospholipids? Describe in brief the different classes of phospholipids.

8. a) Differentiate between nucleosides and nucleotides and illustrate your answer.
b) Name and describe the experiment which proved that ‘DNA is the material that communicates the genetic information’.

9. a) What are coupling reactions? Explain their significance in biochemical reactions.
b) Write the mechanism of conversion of G-3-P into pyruvate.

10. a) What is substrate chanelling in Kreb’s cycle? Explain.
b) Compare the degradation and the biosynthesis of fatty acids.

BCHET-149 Assignments Details

University	:	IGNOU (Indira Gandhi National Open University)
Title	:	Molecules of Life
Language(s)	:	English
Code	:	BCHET-149
Degree	:	BSCG
Subject	:	Chemistry
Course	:	Discipline Specific Electives (DSE)
Author	:	Gullybaba.com Panel
Publisher	:	Gullybaba Publishing House Pvt. Ltd.