Name: Cell and Molecular Biology
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IGNOU MBC-02 Cell and Molecular Biology - IGNOU Solved Assignment (Latest)

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IGNOU MBC-02 (January 2025 – December 2025) Assignment Questions

1. a) Define the following terms:

i) Nucleoplasm

ii) Mitochondrial cristea

iii) Photosynthesis

iv) Microtubules

b) Write a brief account note on extracellular matrix (ECM).

2. Describe the different cell adhesion molecules.

3. a) What are the check points? Describe their role in regulation of cell cycle.

b) Differentiate between apoptosis and necrosis.

4. a) Discuss the Singer and Nicholson’s Model of Plasma membrane.

b) Explain:

i) Cot Curve

ii) Pseudogenes

5. a) What are the different levels of packaging of DNA into higher order structures? Discuss.

b) Elucidate the rolling circle mechanism of DNA replication.

6. Explain the structure and functions of the following:

a) Helix-Turn-Helix (HTF) motif.

b) E. Coli DNA polymerase III

7. a) Briefly discuss the structure and roles of E. Coli. RNA polymerase.

b) Elaborate the post transcriptional RNA processing in eukaryotes?

8. a) What is Wobble hypothesis? Write its significance.

b) Describe the steps involved in the initiation of bacterial translation

9. Write a short note on the following:

a) Mutation

b) Catabolite repression

10. a) Describe the modifications in DNA and Histones.

b) Discuss the regulation of gene involved in organism development.

IGNOU MBC-02 (January 2024 – December 2024) Assignment Questions

PART-(A)

1. a) Name the cell organelles involved in following functions:

i) Drug detoxification
ii) RNA synthesis
iii) Protein Sorting
iv) Intracellular digestion
v) Citric acid cycle

b) Explain how microtubules assembly and disassembly.

2. a) Discuss collagen as an extracellular matrix molecule.
b) Explain in brief the structure and role of gap junctions.

3. a) What are the chromosomal changes during mitosis? Discuss it.
b) Explain the synaptonemal complex with the suitable diagram.

4. a) Write a brief account note on factors that affects the membrane fluidity and permeability.

b) Explain the following:

i) C. Value Paradox
ii) Monocistronic genes

5. a) Describe the chromosome bonding patterns.
b) Enlist the name and function of the enzymes involved in DNA replication.

PART- (B)

6. a) Explain the mechanism of interaction between DNA binding proteins and Nucleic acid.
b) Differentiate between Zing-Finger motif and Leucine zipper motif

7. a) What are the basic transcriptional unit of E.Coli ?
b) Discuss the upstream and internal promotes of eukaryotic transcription.

8. a) Write about the nature of genetic code and its significance.
b) Explain the process by which amino acids are activated for protein synthesis.

9. Write a short note on the following:

a) Recombination repair
b) Lac Operon

10. a) Describe the RNA editing.
b) Discuss the translational control in eukaryotes.

MBC-02 Assignments Details

University	:	IGNOU (Indira Gandhi National Open University)
Title	:	Cell and Molecular Biology
Language(s)	:	English
Code	:	MBC-02
Degree	:	MSCBCH
Subject	:	Biochemistry
Course	:	Core Courses (CC)
Author	:	Gullybaba.com Panel
Publisher	:	Gullybaba Publishing House Pvt. Ltd.