Name: Parasitology
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IGNOU MZOE-01 (January 2025 – December 2025) Assignment Questions

1. Describe the course of parasitic infection along with the importance of each stage.

2. Define hypersensitivity. Explain various types of hypersensitivity response in the host.

3. Explain the erythrocytic cycle of Plasmodium in human beings. How is this different in different species of Plasmodium?

4. Discuss the pathogenicity of Leishmania spp. Write symptoms and distinct features of each manifestation.

5. Give an elaborate account for diversity and distribution of sleeping sickness in current scenario.

6. Draw neat and labelled diagrams of:

a) Tail end of the male Ancylostoma duodenale.

b) Buccal cavity of adult Ancylostoma duodenale.

7. Differentiate between the following pairs of terms:

i) Acute amoebic dysentery and Chronic amoebic dysentery

ii) Invasive and Non-invasive trophozoites of Entamoeba histolytica

iii) Cell mediate immunity and Humoral immunity in Entamoeba histolytica infection

iv) Contact carriers and convalescent carriers

8. What role does Wolbachia play in the inflammatory reaction in filariasis? List the cytokines and immunoglobulins produced in human beings as an immunity response to filariasis.

9. Why is plague also called ‘Black Death’? Explain the transmission of disease in animals, different forms of the disease and its diagnosis.

10. Write any five properties of an ideal antiparasitic drug treatment.

IGNOU MZOE-01 (January 2024 – December 2024) Assignment Questions

1. What are the main advantages and disadvantages of a parasitic life cycle? Explain.

2. a) What are the different stages of infection, once it sets in the host? Describe briefly.
b) Mention briefly various biochemical adaptations in parasites.

3. a) Explain asexual cycle of Plasmodium in man.
b) Elaborate on the ways of evading the action of host immune system by Leishmania.

4. i) Write a note on trypanosomes affecting man.
ii) Write different methods of detection of schistosomiasis in humans.

5. Explain the pathogenesis in humans caused by adults and larvae of Ancylostoma duodenale.

6. a) How does immunotherapy with the 45 kDa antigen of T. spiralis work in the murine model?
b) How does cell-mediated immunity play an important role in limiting the invasive amoebic disease and its recurrence in the host?

7. i) What is the preferable time to take blood sample from the patient of filariasis for disease diagnosis?
ii) What are the advantages of antigen detection test in filariasis?
iii) Despite high microfilaraemia infection, the filariasis may not show any symptoms of infection. Give reason.
iv) Write the full form of QSAR, LBDD and SBDD.
v) Name any two biological agents used to control mosquito larvae.

8. a) Explain in detail the life cycle of Dracunculus medinensis.
b) Differentiate between the following pairs of terms:
(i) Acute amoebic dysentery and Chronic amoebic dysentery
(ii) Invasive and Non-invasive trophozoites of Entamoeba histolytica

9. Describe the transmission of Eastern Equine Encephalitis and West Nile Fever in animals and write their symptoms.

10. a) What are the different strategies of host-parasite interaction undertaken by nematode parasites of plants?
b) Write ay five properties of an ideal antiparasitic drug treatment.

MZOE-01 Assignments Details

University	:	IGNOU (Indira Gandhi National Open University)
Title	:	Parasitology
Language(s)	:	English
Code	:	MZOE-01
Degree	:	MSCZOO
Subject	:	Zoology
Course	:	Core Courses (CC)
Author	:	Gullybaba.com Panel
Publisher	:	Gullybaba Publishing House Pvt. Ltd.